Ena/Vasp: Solving a Cell Motility Paradox

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ena/Vasp: Solving a Cell Motility Paradox

Modulating the concentration of the actin-binding protein Ena/Vasp within the lamellipodium of a migrating fibroblast results in marked changes in lamellipodium behaviour and actin network organization at the cell's leading edge. This can explain a cell motility paradox.

متن کامل

Deciduous Leaves: Solving the Triple Paradox

Patterns in the dominance of evergreen vs. deciduous plants have long interested ecologists, biogeographers, and global modellers. But previous models to account for these patterns have signifi cant weaknesses. Bottom-up, mechanistic models – based on physiology, competition, and natural selection – have often been non-quantitative or restricted to a small range of habitats, and almost all have...

متن کامل

CELL MOTILITY Historical Development of Cell Motility

In the first half of the 20 century, it was generally accepted that myosin and actin are proteins specific for muscle, and muscle contractility is a specific interaction of actin, myosin and ATP. It came as a surprise when in 1954 Hoffmann-Berling reported that water-glycerol extracted amnion fibroblasts contract upon addition of ATP. Figures CM1a and 1b show that the elongated fibroblast cells...

متن کامل

Patient autonomy in chronic care: solving a paradox

The application of the principle of autonomy, which is considered a cornerstone of contemporary bioethics, is sometimes in obvious contradiction with the principle of beneficence. Indeed, it may happen in chronic care that the preferences of the health care provider (HCP), who is largely focused on the prevention of long term complications of diseases, differ from those, more present oriented, ...

متن کامل

Solving the Paradox of Multiple IRR\'s in Engineering Economic Problems by Choosing an Optimal -cut

Until now single values of IRR are traditionally used to estimate the time value of cash flows. Since uncertainty exists in estimating cost data, the resulting decision may not be reliable. The most commonly cited drawbacks to using the internal rate of return in evaluatton of deterministic cash flow streams is the possibility of multiple conflicting internal rates of return. In this paper we p...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Current Biology

سال: 2002

ISSN: 0960-9822

DOI: 10.1016/s0960-9822(02)00912-0